Gnotobiotic Core

Managed by Animal Care, the gnotobiotic core at Rutgers University provides investigators with the ability to work with germ-free and SPF mice.  Currently the core maintains a germ-free colony with C57BL/6 GF mice.    Our germ-free mice are completely free of exogenous, bacterial, fungal and viral microorganisms. To ensure they remain free of all exogenous microbes, our germ-free mice are housed in isolator cages and are routinely monitored.   These mice are ideal for the study of the microbiome.    The gnotobiotic core also provides investigators with a laboratory that contains a biosafety cabinet and incubator for experimental needs.

Housing

We have four Allentown Sealed Positive Pressure racks that house up to 48 cages each. These cages enable a germ-free environment at the cage level. The isolator cages are great for experiments as each cage provides its own individual isolated clean micro-environment.  Each cage has its own supply of clean air which is filtered through a HEPA filter.  The sterility of each cage is tested every two weeks.  We have flexible film isolators available for larger mouse colonies and breeding.

Technical Services

Our gnotobiotic core provides following types of technical services to researchers as per their protocol needs:

- colony management and breeding of germ-free and SPF mice

- injections

- bleeding

- identification

- fecal collection

- tissue collection for genotyping

- sterility testing

- sterile supplies for experiments

- health monitoring

- animal husbandry services

Professional Services

Training is available in following two areas:

- hands on training using the isolator cages, isolators, and biosafety cabinet

- hands on training tailored to the lab's needs

Whom to contact

If you have questions regarding above listed technical or professional services, please contact :Amanda Bumber at amanda.bumber@rutgers.edu or call  973-972-9231

For overall facility inquiries, including housing and pricing, please contact: Kay Long at kay.long@rutgers.edu or call 973-972-4331

 

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